| 1 | United States Grand Prix | Phoenix Street Circuit | — | Ayrton Senna | McLaren | Ayrton Senna | Jean Alesi |
| 2 | Brazilian Grand Prix | Autodromo Jose Carlos Pace (Interlagos) | — | Ayrton Senna | McLaren | Ayrton Senna | Nigel Mansell |
| 3 | San Marino Grand Prix | Autodromo Enzo e Dino Ferrari | — | Ayrton Senna | McLaren | Ayrton Senna | Gerhard Berger |
| 4 | Monaco Grand Prix | Circuit de Monaco | — | Ayrton Senna | McLaren | Ayrton Senna | Alain Prost |
| 5 | Canadian Grand Prix | Circuit Gilles-Villeneuve | — | Nelson Piquet | Benetton | Riccardo Patrese | Nigel Mansell |
| 6 | Mexican Grand Prix | Autodromo Hermanos Rodriguez | — | Riccardo Patrese | Williams | Riccardo Patrese | Nigel Mansell |
| 7 | French Grand Prix | Circuit de Nevers Magny-Cours | — | Nigel Mansell | Williams | Riccardo Patrese | Nigel Mansell |
| 8 | British Grand Prix | Silverstone Circuit | — | Nigel Mansell | Williams | Nigel Mansell | Nigel Mansell |
| 9 | German Grand Prix | Hockenheimring | — | Nigel Mansell | Williams | Nigel Mansell | Riccardo Patrese |
| 10 | Hungarian Grand Prix | Hungaroring | — | Ayrton Senna | McLaren | Ayrton Senna | Bertrand Gachot |
| 11 | Belgian Grand Prix | Circuit de Spa-Francorchamps | — | Ayrton Senna | McLaren | Ayrton Senna | Roberto Moreno |
| 12 | Italian Grand Prix | Autodromo Nazionale Monza | — | Nigel Mansell | Williams | Ayrton Senna | Ayrton Senna |
| 13 | Portuguese Grand Prix | Autodromo do Estoril | — | Riccardo Patrese | Williams | Riccardo Patrese | Nigel Mansell |
| 14 | Spanish Grand Prix | Circuit de Barcelona-Catalunya | — | Nigel Mansell | Williams | Gerhard Berger | Riccardo Patrese |
| 15 | Japanese Grand Prix | Suzuka Circuit | — | Gerhard Berger | McLaren | Gerhard Berger | Ayrton Senna |
| 16 | Australian Grand Prix | Adelaide Street Circuit | — | Ayrton Senna | McLaren | Ayrton Senna | Gerhard Berger |